Global power dynamics in Southeast Asia have undergone significant transformation in recent years. With the emergence of various new challenges, this region has become the focal point of strategic competition between major powers such as the United States and China. China’s increasing influence, both through the Belt and Road Initiative (BRI) and strengthening military power in the South China Sea, is creating tensions among countries in the region. Southeast Asian countries, such as Indonesia, Malaysia, and the Philippines, must navigate these dynamics while maintaining their sovereignty. The wave of investment from China also brings new challenges to governments in Southeast Asia. China’s infrastructure projects are often accompanied by binding debts, posing a threat to regional economic stability. Some countries have difficulty repaying debts, creating dependency on China. Meanwhile, investment from the United States seeks to increase its influence, often through aid programs and military cooperation. The climate crisis is another challenge facing the region. Countries such as Thailand and Vietnam are particularly vulnerable to natural disasters due to climate change. International collaboration is important to overcome environmental issues that can affect political and economic stability. Regional cooperation through ASEAN can be a platform for creating more effective policies to deal with the impacts of climate change. On the social side, issues such as radicalization and terrorism continue to pose a threat to security in Southeast Asia. In facing this challenge, countries in the region need to increase intelligence cooperation and build programs for deradicalization. The spread of misinformation via social media is also a problem that requires special attention, because it can trigger social tension. The digital economy is also a challenge and opportunity for Southeast Asia. Technological developments have created new jobs but also changed the way business is done. Countries must adapt quickly to these developments, including in tax and data protection policies. The fast-growing startup ecosystem in countries such as Singapore and Indonesia shows great potential, but also requires clear regulations to maintain fairness in the market. However, in facing these various challenges, Southeast Asia has the opportunity to strengthen cooperation between ASEAN member countries. Through multilateral diplomatic activities, countries in the region can create collective solutions to issues faced together. Approaches such as dialogue forums can open up space for the exchange of ideas and more innovative policies. Global power dynamics in Southeast Asia require special attention from all parties involved. With various challenges such as Chinese influence, the climate crisis, radicalization and technological developments, as well as opportunities in regional cooperation, Southeast Asia is at a crossroads that will determine its future direction. It is important for regional leaders to evaluate their position in the ever-changing geopolitical map, for the sake of regional integrity and prosperity.